Good Friday, known locally as 'Viernes Santo', is a significant holiday in Paraguay and is observed with great reverence and devotion. Considered one of the most fundamental holidays of the Christian faith, this public holiday commemorates the crucifixion of Jesus Christ and his death at Calvary. It is observed during Holy Week as part of the Paschal Triduum on the Friday preceding Easter Sunday.

As a predominately Catholic country, Good Friday is steeped in religious and cultural significance in Paraguay. The day is marked by solemn church services, fasting, and processions in the streets. One of the notable traditions is the 'stations of the cross' reenactments, in which different events from Jesus's trial through to his crucifixion are acted out, serving as a vivid reminder of the suffering and sacrifice that forms the foundation of the Christian faith.

On Good Friday, Paraguay's streets often fall silent as businesses close and people retreat to their homes or churches in a sign of respect and contemplation. After the solemnity of Good Friday, the mood becomes more joyous as Easter Sunday approaches, which celebrates the resurrection of Jesus Christ. Despite its solemn nature, Good Friday is a day of unity and camaraderie, where families gather and communities come together to reflect and commemorate.